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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0b3f753172b55ca86b7a6157e8ee7b30ad04933bbb13966b420099dabace9c' 
  AND token = 'mSdPjvDWq6L3Et4GTnRXETtxpEj8eSwA0U/rNkNa1Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}