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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dedcf7e7d6781aba995b3707a31a266cd95f3e7c159c79da205a9540fcd1518' 
  AND token = 'SR3NFVQPRHg69FNhew/Q6trSUPr+4SMmXpwgcnKLwrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}