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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a61e77944d10e2da468b57945ba69e420273b8b3d339cbe330a21b6f9a4ca1' 
  AND token = '2vqmAx7qgaBc7VumT0eFoQvtu7P9xdoFm4xflFqGtRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}