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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e7e98992c3524592c36754d59e2a81d067c9acb1279159d28d8774b0953c1e' 
  AND token = 'v/4BqA0Xt3p6bvdkbIFDJVGjiO3t9+gxuas8pQE7xTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}