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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc848d210a5b052493f53f9d6e14f1da935818ed6c7374f55c7da35886cd6fc' 
  AND token = 'vR2oPe9a6Sll1EiRrs+flda5X29nmRIMQvKM5gDscXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}