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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb2479089086cf3e1dcf087513079aa5e43be2ea794a6f1ff88a037ad016f37' 
  AND token = 'ihQXTENtnmrnAQ64Ekgs6O23l9wxWiqzvZwz/FDRAhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}