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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a68a8bcea987986b175bf164eff45168efb5677e83643f74110a4545b3a0be' 
  AND token = 'RClBrx6Ej3JvcV/OmpUxapBwJNP2YfkEuj6wBAkMVMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}