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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f81e550dc58aef826887630ab73b6ac73d664bb9b1be3d40fe5386590fa55a' 
  AND token = 'p/bxUJpCcokTHzbxaIPgfV+9lQiJM9z5rgc7mck0FcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}