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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cab32a7d7534084b16de5a60f40b56a1aa0e89ab40144e00f30dcc258640a68' 
  AND token = 'mt62J1lQld61Z13dT778TYaZJK329I+/23gptfAWlV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}