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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4898f08bed232643876828eb25f7335da11cef2e90389d23a760acd44fce1ae4' 
  AND token = 'Gg2uC4xci7z8xaYyMOIm6x2Me2HW49lL6bW3MS/M/Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}