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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f096b31bc61c5a132de5a0a3f9f1277904f2d39602ce6644e6f8498385ead30' 
  AND token = '4n1B3pBN2+AYI6RqefUw6e2sbOKmUaoie5TA+Ktcf8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}