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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465b71362a0724ac41dc0bdf6aa6b7701527f6e4e9abb4cac48f5f560eee433c' 
  AND token = 'QyEOLK+PJnIbxZSZ/y7dilRRuVmOISif6qA1rfbBivI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}