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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8681966b8b42548bf2c1d89da602a1071ccc717ba5085156d7d7e1d37b87dc56' 
  AND token = 'mO1/hhA28kid4Y7/ZhtTkCQIsyA6qMN4U0FeGrfSsIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}