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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b3b214528f505ad401c252193fcee88bca6b0de2f3eb30629167f855e8f482' 
  AND token = 'EBinYJYuIHbarGTRcXqDU/VsbNTQbQdoWskCs5gUdtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}