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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c333d3eeb75d79ea8df3dbaedd28f977f1c7df9093637e24d302d49654fa419' 
  AND token = 'JJ3VVayAYQJDV8ih8c0uuTQkZihlgs5Mp8xuad8tOx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}