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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd759f8631cfea7d11a1e6dce6e5bf72b1d6236e7ddb86faf21962820dbf565' 
  AND token = 'yKC71ZB/H8TOPZ4TcSO7nrAwn/JBy0Ll53Z5S/DHBPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}