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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f47d4592d7867fdb8cf393e78148fa970ae91e905b28ddf4ffd766e153152024' 
  AND token = 'I2N4kgAa6a7VyPw9+nfwfa2PTQ/tmf3NXYwRnLEV/7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}