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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14336caa0611a2540ab05f309112734346be6fde11d2a49b71d3bc88bbee4d9' 
  AND token = 'fcDGasvQIdDWOO9LGP4PeqcpY0AA1VUIF+8cni8AMpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}