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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b4ea1935e44943d23503ed39b8930fdc1587e036e20585dab4820f2f147b56' 
  AND token = 'tR6AFxl2FsdsVMB7MDn4G87qipEP42PvcVhQdpxefvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}