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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede7e00378e103db9f70c7ea7dccee30fa9e559d972c9d016ba1788e3d3b05d6' 
  AND token = 'Qddd+6qkHGDV03QzwlMfurUk9wV/6Pb+0lNAi0C+gNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}