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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c9dd821fe44fb90f48e3af55dc8811599942526659c681a6809b3c9c857871' 
  AND token = 'rm/V8qqLXIKxcKc+tzBEreL/WU0HaXS99uw+HLKrQWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}