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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d0f2351ae25cb0f2a5bbe37c4b2b0fec5ff492d9a973201186ae8ef98fde66' 
  AND token = '0Hh9niLSH8aKYBLUyMyrCl9s9pT/vVl1WMpyXg7dYkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}