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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd56f44afa9af842e221a7a76668aa67e4ec6fc03d18edcc052b022d62bf82611' 
  AND token = 'PV0GllRN3QwbbQADjUCQS3nBxgnAJ0DvaDC6peXLBIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}