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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535ffcd1ef35fae70e81f25b649c5b6720c72deb8490cdd0870ff0cd9ecaccea' 
  AND token = 'CcXDdkPmUUU/YfVQ+4t+sDHD6IdjQb5E7r1og7tCETI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}