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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43854a4922a6c4009ca435056c65c5325d18ebfc3bb92c688336b1bfa231107d' 
  AND token = 'UwSxEc7JC8hlj5NnL6RK786cp8Ey4WkeIdz3RjEN1lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}