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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2421a8a334044119eff82f7266c5e687d67534fde07f4403e76d039a3b3cb798' 
  AND token = '4t4GlMpZ7kNyeVoKtKuLr28Q6S4EDHWGZq4CmgAduH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}