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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb9f440658c39fefec9cfc28e2fdaf3bc6b5337e9fb2740698adee886d9f569f' 
  AND token = 'IizTR9Fb2CdncM5Itgf8nkDIHs/PF1U8/I9Aac/1GQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}