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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc87b8a7b763ebd7c96ba0988b088e24a67f1feacf131286b42140e9e53f3bf' 
  AND token = '6uiFYN4/9Hm+HZzYMXo4k3a+oZSZHjBk9Q/3mftnkgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}