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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb2a97bf09daeffa6440b8b7223106f3b42d6e932c6e12ad109eaa00072b1f28' 
  AND token = 'x6Hj1RqlUZoxtRG+xvcAJ6pWwXGNDCcyWqR8oNza5nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}