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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a81018f1119554874b3075085edcfd96cfd565f19aec491de4b87a595d01240' 
  AND token = 'Qu5x2QE4R9OSIc1v+gKfe1ICaW8QvKiVkgwdn4pCOn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}