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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b65ccf41561b8b787665f801e639da3a39ff64704398cdf6727ddec9af615b9' 
  AND token = 'kXbQpVT8BKv4Fh6T/7FOXWe2j18Px3MYpTb20uLZE6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}