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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809b339bf62ab5a89896e3b1ff8e5eff8a2721f21f6720b725f668af2c720782' 
  AND token = 'BGfm+LnD/Ow/0VBXxRm2iwyClxEw5164sRmplDWwOxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}