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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edef4d70ce07c37f022c45bfbb9a2745b78fddf3359fabbc71a878df777cf48f' 
  AND token = 'Q3H3seXmzdR+sZdGuK9iTX+29J2zLXhUmEp6l+P/RGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}