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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c288b00ffb6052aaf9783c9e4188573ecbb7336d697024d193a762d92cb17eca' 
  AND token = 'bLqEdb3i0HrEt7Uk+Htg6nwfXufdMZFtSoupjODKW6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}