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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f66a7f0a1f0e647812060aa0e95a9946b8c3c77475dfe57595bca7cfed436a3' 
  AND token = 'qjTTWZrkepR4n93nW7Zmff60pF+c6OdRM01LD2HsHu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}