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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b7e0b2cb27802838b7786ff6c95f38cc595f0bb9b6b7d47c67a433a886ec823' 
  AND token = 'ly4PIYUx/rgsOWA+w8UNcMcF7nfEK2yjkwXA/zh/KQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}