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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c02f974f1323296608b89bb379cd954e99aa58062c8e3307ba0a59c3473ec3af' 
  AND token = 'UYxgbhyGChGU7G7s8S2CgsQ29Zo56kN+Tt21HQvvyC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}