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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd6b54910c9e41df3923d45075a799b0f8c4973c0c767b3f76b306083d24d01' 
  AND token = 'egeI6ppvUzRTfo2W6EEv1TwrCBHlJId/FWdIIGYFokQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}