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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7447c247e9f53a21d0c4de31b69d6ffe6d8fcd4f50d2a089e48123f4ca2035a4' 
  AND token = 'rNCEo77Q6T0E7+QJtAVzy5XkbYDb1GZIL76eO9HzbQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}