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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c77a6c780511217f02b92e31b41c19be4879506abf6133b260608942607122' 
  AND token = 'oV5r6K9/nQw2TujiIJ197fRvOXwCbHYgvEvQfEqwuyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}