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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '310db62c6f76fe9e6e180bc670b4e89c74028307bf59e0c15f8001b3dd63c0e5' 
  AND token = 'ZXN7oGqPQopO30CWUym0IbY3IoQdlYUlayyTmZIdM20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}