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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd0d12b08f7cd26dbc9847ff51707dec9e98503d3353815743fd2bf6c1c852a5' 
  AND token = '8MB/+9A8NMY/VK1KdQqRWU1R14lbehn/kbFLN0mgUDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}