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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe360a1d1c6ad28143a87d48ef9f811d4e4546d59408adb5e7c6e1dea8d836cc' 
  AND token = 'n3tpx7vJ2vwyEEOEoucB+unWtHXuSOEKsJnAKkSkG4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}