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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de85f7229586f26a1cc3b18c3681c2475e93b4b50c2f0aec8a6271e5251586ab' 
  AND token = 'yTrUjfEqev5P8twtBbqi+hsJBfUge1kcWYbulNkcv1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}