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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52105eb7188e5d3254712c4dc5a9cca15fd8b4675d9e8d1c25176f5e22fdd42' 
  AND token = 'tqWuRlNGR5mOnVdTnYkYbypggAZbJNLtPn/ZI5AMxHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}