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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f7f40cc6c104e98082edac69131866ad3bfc49974f99860353af6c3a6eb983' 
  AND token = 'R3OaxvrJudHE+rk0+4yDpxx92Ffr1WzMcHmXtY2bi3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}