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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7182a21fa94abbd23e8679c252d6bafb6e9e0b43cf64997529ca6b169fca971a' 
  AND token = 'tImd7LcCcRnAW/eU3yFa06D9Kge5AfgoFwi2R7FUr9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}