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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67245389c8b86d12855167d47cdb900c51b4020b456618a34d67203ac6522511' 
  AND token = 'eKyULAegfiPnd8R5FX8XSY+P/3B7wCcH4RXzkT/n2Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}