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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81e8a4021363a9c7838558ffc381a00faf8f0a6a59e35ba33442eb7a94f51ab' 
  AND token = 'hgEm4vTyOiklIQfogcuDjnhrlbArw0vXnKnj9qsHLT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}