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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e77c23593141ede5e951e72dbec3c59888e164ae4e86e95510f8abda72c7286' 
  AND token = 'BIo30xGl55Qr+eS53C9ScWUYLO3VJfOR6kVKq6KkfF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}